What is Amniosynthesis? Curious About Amniosynthesis

The pregnancy period covers a 9-month period that occurs naturally. In some cases, problems caused by diseases or pregnancy that are already present in the body of the mother before pregnancy occur can cause some risks.

Pregnancies in this condition are called risky pregnancy or high-risk pregnancy.

Screening tests performed within certain processes during pregnancy generally provide an idea of the course of pregnancy. When the results of screening tests such as double testing and triple testing are at risk, doctors often direct pregnant women to methods used for definitive diagnosis.

Amniosynthesis is a procedure that results in close to 100% accuracy about the health of the baby in risky pregnancies.

Purpose of Amniosynthesis
Amniosynthesis was previously used to evaluate the baby’s lung functions and to determine the amount of jaundin in the baby in the presence of blood mismatch. In today’s conditions, it is often applied in the womb for the examination of the chromosomal structure of the baby.
Apart from chromosome analysis, amniosynthesis can also be applied to treat the baby called ‘polyhydramnios’ in cases where the water is high.

In which cases can Amniosynthesis Be Performed?
• Amniosynthesis can be considered in case of high-risk results from screening tests during the first trimester period of pregnancy.
• Amniosynthesis can be considered in the event of any chromosome abnormalities in one of the biological parents.
• Amniosynthesis may be considered in the event of chromosomal disorders in one of the parents that do not affect them but are likely to affect the baby.
• In women under 17 years of age and over 35 years of age, amniosynthesis may be considered due to the high risk of chromosomal abnormalities.
• Amniosynthesis may be considered if one of the parents or close relatives has a central nervous system defect such as spina bifida.
• Amniosynthesis may be considered by pregnant women in the event of a pregnancy that has previously experienced a complication such as chromosomal anomaly or neural tube defect.
• Amniosynthesis can be considered if it is known that parents are carriers of genetic mutations that cause the disease, such as single gene disorders.
• Amniosynthesis can also be considered if the expectant mother has a male relative with hemophilia or other gender-based genetic disorder.

When Can Amniosynthesis Be Applied?
The process of mniosynthesis, which is applied to diagnose chromosomal anomalies, is 16-22. can be applied between weeks. However, in clinical practice, it is often 17-18. it is preferable to be applied in weeks.
On the 16th century of the amniosynthesis process, earlier than the week of pregnancy can increase the risks associated with the baby. After amniosynthesis after the 20th week of pregnancy, the pregnancy will not be legally intervened as it takes 2-3 weeks to detect chromosome disease.
The legal limit for termination of pregnancy due to chromosomal abnormalities is 24. It ends in the week.

How to Apply Amniosynthesis?
It is very important to examine and evaluate the pregnancy and baby in detail with ultrasound before amniosynthesis is performed. During the week of pregnancy, fetal posture position, determination of suitable fluid pockets, and baby-related evaluations such as the placenta’s settlement should be determined.
Before the amniosynthesis process, the presence of masses or ovarian cysts such as myoma salutations in the uterus should also be examined. In addition, the length of the cervix, known as cervical length, should be considered and the risks of low and premature birth should be taken into account.

Amniosynthesis is a surgical procedure that does not require anesthesia. Sometimes the skin can be drugged with local anesthesia before amniosynthesis, but since amniosynthesis is completed with only one needle input, there is no reason to inject for local anesthesia before the procedure.
In order to reduce the risk of infection after amniosynthesis, the abdominal skin before the procedure should be cleaned with special solutions and sterilization should be provided in the region. Then, with ultrasound, the amniotic fluid is reached by advancing through the uterine wall with the help of a needle that is very thin at a thickness of 20-22 gauge.

With the help of an injector attached to the tip of the needle, the first 2-3 ml liquid taken from the amnihiate fluid does not participate in the evaluation due to the cells that will be transmitted from the womb. A total of 15-20 ml of amniodofluid is then drawn to 2-3 injectors.

Normally, the anion fluid is clear and light yellow. However, amniotic fluid taken during amniosynthesis can sometimes be tainted with blood. This condition does not harm the baby, but it can affect the accuracy of the result.

After the liquid is removed, the amniosynthesis needle is removed after the baby is checked by ultrasound. Amnion fluid containing the baby’s cells is sent to the laboratory as soon as possible for examination.

Is Amniosynthesis a Risky Procedure?
Vaginal bleeding and cramping in the style of staining within a few hours after amniosynthesis process is considered normal. In case of fever, tremor, water coming, bleeding and contractions, it is necessary to consult a doctor after amniosynthesis process.
Since it is necessary to enter the baby’s pouch during amniosynthesis process, a miscarriage may occur due to injury and infection that may occur after the procedure. The low risk due to amniosynthesis is less than 1%. It can be seen in 1 out of 200-300 pregnancies on average.

Mothers who perform amniosynthesis have a risk of serious infection due to processing of less than 0.1%. Infection may be caused by damage to the intestines during the injection of the needle or the effect of germs on the skin. However, the risk of infection is very low if the sterilization criteria are met while amniosynthesis is performed.
The arrival of water from the entrance or vagina of the amniosynthesis needle is a very frightening condition for expectant mothers. This fluid leaks from where the needle pierces the gestational sac, in which case the doctor who performs the procedure must be informed. The arrival of water will often stop spontaneously in a few days.